Are Biosimilars Identical to the Reference Products?

are biosimilars identical to the reference products?

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The Development of Botanical Products with Special Reference to Seri-Ecosystem

The search for alternative ways of controlling sericultural pests has led to the investigation of plant sources for naturally occurring compounds which may have Insect growth regulatory, feeding deterrency, repellency and confusantcy characteristics. More than 2000 species of the families Asteraceae, Fabaceae and Euphorbiaceae are known that possess some insecticidal activity. Plants with inse...

Antibodies to infliximab in Remicade-treated rheumatic patients show identical reactivity towards biosimilars.

OBJECTIVES The aim of this study was to determine whether antibodies to infliximab (IFX) in Remicade-treated patients cross-react with the biosimilar CT-P13. METHODS 250 consecutive patients with rheumatic diseases under Remicade and 77 controls were retrospectively selected for the study. Anti-IFX antibodies at drug through levels were measured in parallel with three different bridging ELISA...

Switching Reference Medicines to Biosimilars: A Systematic Literature Review of Clinical Outcomes

INTRODUCTION To evaluate the possibility that switching from reference biologic medicines to biosimilars could lead to altered clinical outcomes, including enhanced immunogenicity, compromised safety, or diminished efficacy for patients, a systematic literature review was conducted of all switching studies between related biologics (including biosimilars). METHODS A systematic search was cond...

Canada's approach to biosimilars questioned.